How to install an SSD on your PC

NVME drive not working in second slot of Asrock B450 m 2 sata slot on motherboard Can MSI B450 Tomahawk MAX II run SATA and NVMe SSD on the slot and what is the m2_1 slot : h81 motherboard with nvme slot

m2 pcie slot When the motherboard slot M2_1 is used, two SATA 6 Gbs ports are disabled What would this mean?